Malwarebytes is an anti-malware software that offers protection against malware, ransomware, and other online threats.
Starting from $39.99/year
Best Microsoft Defender for Business Alternatives ranked by AI · updated Aug 2026
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Microsoft Defender for Business provides endpoint protection and security management for small and medium-sized organizations. It integrates closely with Microsoft 365, Entra ID, Intune, and other Microsoft security services.
Developer: Microsoft
Price: From $3/user/month
🎯 microsoft.com/en-us/security/business/endpoint-security
Top 6 Microsoft Defender for Business alternatives
SentinelOne is an autonomous endpoint protection platform that prevents, detects, and responds to attacks across all major vectors.
Contact for pricing
Sophos provides endpoint, firewall, email, and managed cybersecurity products for businesses of many sizes. Its standout capability is integrated protection managed through...
Pros
- Broad endpoint, firewall, email, and cloud security portfolio
- Centralized management is more mature than many SMB tools
- Sophos MDR adds human-led monitoring and response
Cons
- Can be more complex and expensive than Bleach Cyber for very small firms
- Advanced features often require higher-tier subscriptions
- Some administrative workflows are designed for IT professionals
CrowdStrike Falcon is a comprehensive endpoint security solution that offers advanced threat detection and response capabilities.
Available upon request
ESET PROTECT is a centralized security platform for managing endpoint, server, and mobile-device protection across business environments. Its Advanced protection tier adds...
Pros
- Combines endpoint management, detection, and policy control in one console
- Strong malware detection with low resource usage
- Supports cloud or on-premises management deployments
Cons
- Advanced features require higher subscription tiers than basic endpoint protection
- Less widely integrated with identity and productivity suites than Microsoft Defender
- Pricing is less transparent than many SMB-focused competitors
Quote-based annual subscription
Webroot Business Endpoint Protection is a cloud-managed endpoint security platform for small and mid-sized businesses. It uses lightweight agents, cloud-based threat analysis,...
Pros
- Uses less endpoint resource capacity than many traditional antivirus suites
- Cloud-based console simplifies deployment and policy management
- Fast scans and rollback capabilities help reduce disruption from malware
Cons
- Less comprehensive identity and extended detection coverage than CrowdStrike or SentinelOne
- Advanced investigation and threat-hunting features are limited
- Pricing is not transparent and typically requires a reseller or sales quote
Quote-based
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