SecureAPlus is a security software that combines antivirus, anti-malware, application whitelisting, and cloud antivirus.
Free basic version, paid plans available
Best ThreatLocker Alternatives ranked by AI · updated Aug 2026
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ThreatLocker is a cloud-managed endpoint security platform with application allowlisting, ringfencing, storage control, and elevation management. It is built for managed service providers and organizations that want centralized control over what software can execute and what resources it can access.
Top 6 ThreatLocker alternatives
2
Applocker
Microsoft
AppLocker is a Windows application-control feature that lets IT administrators define which executables, scripts, installers, and packaged apps users may run. It...
Pros
- Built into supported Windows Enterprise, Education, and Server editions
- Uses publisher, path, hash, and user or group-based rules
- Integrates with Windows Group Policy and event logging
Cons
- Less sophisticated cloud management than dedicated application-control platforms
- Rule maintenance can become labor-intensive in large environments
- Limited cross-platform support compared with commercial competitors
Included with supported Windows editions
CyberLock is a Windows application-control tool that blocks untrusted executables and scripts from running. It is aimed at home users and small...
Pros
- Blocks unknown executables before they run
- Lightweight compared with many managed endpoint platforms
- Can protect against ransomware variants that evade signatures
Cons
- Windows-focused with no comparable macOS or Linux client
- Manual trust decisions can interrupt software installation and updates
- Fewer reporting and policy-management features than ThreatLocker or Airlock Digital
Application Control Plus is an endpoint application control and privilege management platform for IT and security teams. It supports application allowlisting, software...
Pros
- Combines application control and privilege management in one console
- Supports policy-based allowlisting and software restriction
- Integrates with other ManageEngine endpoint management tools
Cons
- Less established in privilege management than BeyondTrust or CyberArk
- Configuration can become complex in large, diverse environments
- Pricing is quote-based rather than transparently published
Microsoft Intune is a cloud-based endpoint and mobile device management solution that integrates with Microsoft 365.
Pros
- Integration with Microsoft 365
- Granular control over devices
Cons
- May require additional Microsoft licenses for full functionality
Starting at $6 per user per month
6
Windows Defender Application Control
Microsoft
Windows Defender Application Control is Microsoft's policy-based application and code-integrity control for Windows devices. It is aimed at security teams that need...
Pros
- Provides stronger code-integrity enforcement than AppLocker
- Supports signed-code and managed-installer policies
- Integrates with Microsoft security and device-management tooling
Cons
- More complex to design, test, and troubleshoot than AppLocker
- Policy deployment can require Intune, Configuration Manager, or custom tooling
- Primarily focused on modern Windows environments
Included with supported Windows editions
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